Effects of Pesticides, Herbicides and Fertilizers
Every pesticide and every herbicide ever tested has non-target organism effects. It is rare that scientists make such blanket statements, but in this case, it is true. Most pesticides are not as detrimental as methyl bromide, for example, but while each application may impact only a few species, the cumulative effect of multiple and repeated pesticide applications has been a loss of the soil's ability to maintain life. The Bulletin of Environmental Toxicity, as well as Soil Biology and Biochemistry, Applied Soil Ecology, and Biology and Fertility of Soil, have numerous papers documenting many of these direct and indirect pesticide impacts. See the papers by E.R. Ingham documenting impacts of many pesticides.

Fertilizers kill soil organisms too, but typically it is the result of osmotic shock (salt effect) when more than just a few pounds per acre are applied at a time. Fertilizer additions work best when there is a healthy foodweb in the soil helping to move those nutrients to the plant, and less damage occurs when small quantities of fertilizer are added at any one time. Thus, care is required to protect the helpful organisms in the soil.

 

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